0

Full Content is available to subscribers

Subscribe/Learn More  >

Destruction of Definity® Microbubbles Used for Ultrasound Imaging and Drug Delivery

[+] Author Affiliations
Kausik Sarkar, Pankaj Jain, Dhiman Chatterjee

University of Delaware

Paper No. IMECE2004-61646, pp. 229-235; 7 pages
doi:10.1115/IMECE2004-61646
From:
  • ASME 2004 International Mechanical Engineering Congress and Exposition
  • Fluids Engineering
  • Anaheim, California, USA, November 13 – 19, 2004
  • Conference Sponsors: Fluids Engineering Division
  • ISBN: 0-7918-4709-8 | eISBN: 0-7918-4178-2, 0-7918-4179-0, 0-7918-4180-4
  • Copyright © 2004 by ASME

abstract

Microbubble based contrast agents improves medical ultrasound images. Destruction of contrast agent Definity® (Bristol Meyer-Squibb Imaging, North Ballerina, MA) is studied using broadband attenuation technique. Single-cycle ultrasound pulses are sent through a bubble suspension at different pulse repetition frequencies (PRF) and pressure amplitudes. For each PRF, there is a critical pressure amplitude (~1.1–1.2MPa for 50, 100, 200 Hz PRFs studied), below which there is no evidence of bubble destruction. Above the critical pressure amplitudes the rate of destruction depends on PRF and pressure. But at high pressure amplitudes (e.g. 2.97 MPa) destruction becomes independent at higher PRFs.

Copyright © 2004 by ASME

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In