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Simulation of Red Blood Cell Deformation in Microvessels Using a New Rapid Modified Particle Method

[+] Author Affiliations
K. Firoozbakhsh, M. T. Ahmadian, M. Hasanian

Sharif University of Technology, Tehran, Iran

S. Samiezadeh

Tarbiat Modares University, Tehran, Iran

Paper No. IMECE2011-63540, pp. 1087-1090; 4 pages
  • ASME 2011 International Mechanical Engineering Congress and Exposition
  • Volume 6: Fluids and Thermal Systems; Advances for Process Industries, Parts A and B
  • Denver, Colorado, USA, November 11–17, 2011
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5492-1
  • Copyright © 2011 by ASME


The deformation of human red blood cell has been a topic of considerable scientific interest and real-life significance. Several methods have been improved to simulate the behavior of red blood cells motion and deformation in micro-capillaries. Since in microscopic scales, using discrete models are more preferred than continuum methods, moving particle semi-implicit method (MPS) which is one of the recent innovative particle based methods, can simulate micro-fluidic flows based on Navier-Stocks equations. It has been shown that original MPS method has a lack of rapid calculation which leads to massive calculations and long time simulation. Quite a few studies have been done to improve MPS method. But the main problem, calculation of viscosity effect in conjunction with fluid pressure distribution, is still under discussion. In this paper a new algorithm is proposed that is to say by this method simulation duration decreases by the factor of 20 while the accuracy of the results remains constant. The results indicate that while the velocity precision is as well as original method, the duration of simulation is reduced more than 20 times. This significant novel MPS algorithm can be implemented in future studies for simulation of multi-fluid flows, complex geometry flows and micro-scale biomedical phenomena.

Copyright © 2011 by ASME



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