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Hydrodynamic Focusing Based Particle Filtration Using an Island Structure With Built-In Valves

[+] Author Affiliations
Kangsun Lee, Byungwook Ahn, Kwang W. Oh

The State University of New York at Buffalo, Buffalo, NY

Paper No. IMECE2009-11312, pp. 687-688; 2 pages
doi:10.1115/IMECE2009-11312
From:
  • ASME 2009 International Mechanical Engineering Congress and Exposition
  • Volume 12: Micro and Nano Systems, Parts A and B
  • Lake Buena Vista, Florida, USA, November 13–19, 2009
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4385-7 | eISBN: 978-0-7918-3863-1
  • Copyright © 2009 by ASME

abstract

We propose a hydrodynamic focusing based particle filtration method. Three microchannels associated for the filtration were networked with an island structure to control a boundary to limit particle sizes. The boundary was easily controlled by adjusting lengths of the three microchannels. Using hydrodynamic focusing in the microfluidic network, we have successfully designed and tested the device to filtrate particles of 10-μm and 20-μm. By adjusting the ratios of hydraulic resistances (or outlet channel lengths) using the built-in valves, the boundary distance was controlled. The proposed method could continuously sort particles by size. Thus, the proposed sorting method can be applicable for many fields for biology and biomedical engineering.

Copyright © 2009 by ASME

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