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Effect of Mechanical Pulse Oscillations on Pre-Contracted Porcine Airway Smooth Muscle

[+] Author Affiliations
S. Theodore, A. M. Al-Jumaily, P. Mbikou

Auckland University of Technology, Auckland, New Zealand

Paper No. IMECE2011-63154, pp. 649-650; 2 pages
  • ASME 2011 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
  • Denver, Colorado, USA, November 11–17, 2011
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5488-4
  • Copyright © 2011 by ASME


This research focuses on investigating the effect of pulse oscillation rather than sinusoidal oscillation on contracted airway smooth muscle (ASM). Isolated ASM were tested using pulse oscillations with Frequency of 0.5 Hz, 1Hz and 2Hz; Amplitude of 2%, 4%, 6% and 8%, and duration of 1 min, 2 min and 3 min (n = 5). Results obtained from the experiments showed that pulse oscillation with short duration had significant effect on the relaxation of ASM compared to sinusoidal oscillations with longer duration.

Copyright © 2011 by ASME
Topics: Oscillations , Muscle



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