Full Content is available to subscribers

Subscribe/Learn More  >

Microfluidic Chip for Particle-Liquid Separation

[+] Author Affiliations
Priyank Bhardwaj, Piyush Bagdi, Ashish S. Sharma, Ashis K. Sen

Indian Institute of Technology Guwahati, Guwahati, AS, India

Paper No. IMECE2011-62343, pp. 391-398; 8 pages
  • ASME 2011 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
  • Denver, Colorado, USA, November 11–17, 2011
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5488-4
  • Copyright © 2011 by ASME


This paper presents theoretical analysis, design, fabrication and test of a microfluidic device (‘Micro hydrocyclone’) for separation of micron and sub-micron size solid particles from liquid in a particle-liquid mixture. A theoretical analysis of the micro hydrocyclone is performed to understand the physics and develop suitable design models. The structure of the proposed device is designed based on Bradley model, as it offers lower cut-size thus making it suitable for microfluidics applications. The operational parameters are derived from the dimensional group model. The device is fabricated with SU-8 photoresist on PMMA substrate using a combination of photolithography and micro-milling. Experiments are performed to demonstrate particle-liquid separation using polystyrene microbeads suspended in PBS as the feed sample. The influence of inlet velocity and particle size on particle separation efficiency is investigated. The proposed device can be easily integrated with micro-environments thus is suitable for lab-on-chip and microsystems development. The device may have applications in chemical analysis, materials research, point-of-care, blood sample preparation and other biomedical applications.

Copyright © 2011 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In