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Monte-Carlo Simulation of Pressure Propagation in Elastic Arteries: Proposing a New Algorithm for the Clinical Assessment of Carotid-Femoral PWV

[+] Author Affiliations
A. Mookerjee, A. M. Al-Jumaily

Auckland University of Technology, Auckland, New Zealand

A. Lowe

Pulsecor Limited, Auckland, New Zealand

Paper No. IMECE2008-66747, pp. 597-598; 2 pages
doi:10.1115/IMECE2008-66747
From:
  • ASME 2008 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology Engineering
  • Boston, Massachusetts, USA, October 31–November 6, 2008
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4863-0 | eISBN: 978-0-7918-3840-2
  • Copyright © 2008 by ASME

abstract

A Monte-Carlo simulation is developed to study the pressure propagation characteristics in a representative healthy randomly selected human population. Normal distribution sets are defined for different anatomic and physiological parameters based on data available in literature. Random input parameter sets are then generated from these distributions. A mathematical model is then used to simulate the pressure propagation characteristics in large elastic arteries defined by these input parameters. The pressure wave characteristics are then analysed to estimate carotid-femoral pulse wave velocity. Predictions closely match clinically observed trends.

Copyright © 2008 by ASME

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