0

Full Content is available to subscribers

Subscribe/Learn More  >

Complexity and Frailty: Multiscale Entropy of Balance Dynamics During Quiet Standing and Dual-Task: The Mobilize Boston Study

[+] Author Affiliations
Hyun Gu Kang

Hebrew SeniorLife; Beth Israel Deaconess Medical Center; Harvard Medical School; Boston University, Boston, MA

Madalena Costa, Ary L. Goldberger, Chung-Kang Peng

Beth Israel Deaconess Medical Center; Harvard Medical School, Boston, MA

Attila A. Priplata

Stryker Corporation, Cambridge, MA

Olga V. Starobinets, Dan K. Kiely

Hebrew SeniorLife, Boston, MA

L. Adrienne Cupples

Boston University, Boston, MA

Lewis A. Lipsitz

Hebrew SeniorLife; Beth Israel Deaconess Medical Center; Harvard Medical School, Boston, MA

Paper No. IMECE2008-68973, pp. 455-458; 4 pages
doi:10.1115/IMECE2008-68973
From:
  • ASME 2008 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology Engineering
  • Boston, Massachusetts, USA, October 31–November 6, 2008
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4863-0 | eISBN: 978-0-7918-3840-2
  • Copyright © 2008 by ASME

abstract

Balance control during standing is attributable to the complex, nonlinear interactions of multiple postural control systems, manifested as the highly irregular displacements in center of pressure (COP) during standing. Aging and associated frailty may result in the degradation of these complex interactions and manifest as a loss of complexity in COP dynamics. Furthermore, frail individuals may not be able to adapt to a superimposed stress that challenges balance, leading to falls. To test these hypotheses, data were analyzed from the MOBILIZE Boston Study, an ongoing population-based study of community-dwelling older adults. Each participant’s frailty phenotype (not frail, pre-frail, frail) was determined using the Fried et al. 2001 definition. 551 participants (age 77.9±5.5) stood on a balance platform, with or without concurrently performing serial subtractions. Complexity of balance dynamics over multiple time scales was quantified using multiscale entropy (MSE), a more sensitive measure of physiologic health than variance. Of the participants, 39% were pre-frail and 6% were frail. Baseline MSE was lower with each successive frailty condition (p<0.002). When performing the cognitive task, MSE was lowered similarly in all groups (p<0.001). Frailty was associated with a loss of complexity in the dynamics of postural sway, which may be due to the degradation of integrated postural control networks that enable upright stance. Performance of a dual-task further reduced this complexity. Cognitive distractions during standing may further compromise balance control in frail individuals, which may explain their increased fall risk.

Copyright © 2008 by ASME

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In