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Deformation Prediction of Mouse Embryos in Cell Injection Experiment by a Feedforward Artificial Neural Network

[+] Author Affiliations
Ali A. Abbasi, M. T. Ahmadian, G. R. Vossoughi

Sharif University of Technology, Tehran, Iran

Paper No. DETC2011-47073, pp. 543-550; 8 pages
doi:10.1115/DETC2011-47073
From:
  • ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference
  • Volume 2: 31st Computers and Information in Engineering Conference, Parts A and B
  • Washington, DC, USA, August 28–31, 2011
  • Conference Sponsors: Design Engineering Division and Computers and Information in Engineering Division
  • ISBN: 978-0-7918-5479-2
  • Copyright © 2011 by ASME

abstract

In this study, neural network models have been used to predict the mechanical behaviors of mouse embryos. In addition, sensitivity analysis has been carried out to investigate the influence of the significance of input parameters on the mechanical behavior of mouse embryos. In order to reach these purposes two neural network models have been implemented. Experimental data earlier deduced-by [Flückiger, M. (2004). Cell Membrane Mechanical Modeling for Microrobotic Cell Manipulation. Diploma Thesis, ETHZ Swiss Federal Institute of Technology, Zurich, WS03/04] –were collected to obtain training and test data for the neural network. The results of these investigations show that the correlation values of the test and training data sets are between0.9988 and 1.0000, which are in good agreement with the experimental observations.

Copyright © 2011 by ASME

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