0

Full Content is available to subscribers

Subscribe/Learn More  >

Study of Structured Porogen Method for Bone Scaffold Fabrication

[+] Author Affiliations
Lin Lu, Peter I. Lelkes, Jack Zhou

Drexel University, Philadelphia, PA

David Wootton

Cooper Union, New York, NY

Paper No. MSEC_ICMP2008-72134, pp. 491-496; 6 pages
doi:10.1115/MSEC_ICMP2008-72134
From:
  • ASME 2008 International Manufacturing Science and Engineering Conference collocated with the 3rd JSME/ASME International Conference on Materials and Processing
  • ASME 2008 International Manufacturing Science and Engineering Conference, Volume 2
  • Evanston, Illinois, USA, October 7–10, 2008
  • Conference Sponsors: Manufacturing Engineering Division
  • ISBN: 978-0-7918-4852-4 | eISBN: 978-0-7918-3836-6
  • Copyright © 2008 by ASME

abstract

The increasing demand on bone scaffolds has promoted the development of tissue engineering fabrication technique for manufacturing bone scaffold. In this study, a novel structured porogen method for bone scaffold fabrication has been explored. This method has demonstrated highly efficient and reproducible fabrication of structured bone scaffolds which mimics the bone structure. By using commercially available Drop on Demand (DDP) system and three dimensional printer (3-DP) system, at first designed structured porogens can be manufactured, and then bone scaffolds can be fabricated by injecting the biocomposite materials into the porogens. The mechanical properties of the fabricated scaffolds using DDP system have been characterized. The biocompatibility of our fabricated scaffolds using 3-DP has been examined. With incorporating of bioactive calcium phosphate into the composite materials, the mechanical strength and bioactivity of the scaffolds made by the structured porogen method can be improved significantly. This structured porogen method has a potential to be used on various Solid Freeform Fabrication systems which allows each system to use a single ubiquitous building material to fabricate multiple biomaterial scaffolds with sufficient mechanical integrity.

Copyright © 2008 by ASME
Topics: Manufacturing , Bone

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In