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Biomechanical Evaluation of Autologous Mesenchymal Stem Cell Transplantation to Improve Fascial Repair

[+] Author Affiliations
Hazel Marie, Diana L. Fagan

Youngstown State University, Youngstown, OH

Jeremy Heffner

St. Elizabeth Health Parners, Youngstown, OH

Paper No. IMECE2009-12466, pp. 97-100; 4 pages
  • ASME 2009 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology Engineering
  • Lake Buena Vista, Florida, USA, November 13–19, 2009
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4375-8 | eISBN: 978-0-7918-3863-1
  • Copyright © 2009 by ASME


Hernia repair continues to be one of the major problems faced by surgeons. Up to 10% of laparotomies are complicated by post-operative incisional hernia, carrying with it a myriad of complications ranging from cosmetic disfigurement to life-threatening strangulation of the bowel [1]. A large percentage of these incisional hernias will recur following surgical repair leading to a more vicious cycle of hernia, followed by repair, followed by hernia. It is therefore imperative to create a more optimum wound-healing environment. The intent of this study was to investigate a novel approach for significantly reducing the initial occurrence of incisional hernia and their associated morbidities, thereby halting the vicious cycle of hernia formation.

Copyright © 2009 by ASME



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