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Application Study of Biomechanical Estimator Using Optical Coherence Straingraphy to Atherosclerosis

[+] Author Affiliations
Yoshitaro Sakata, Souichi Saeki, Takashi Saito

Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan

Takafumi Hiro, Masunori Matsuzaki

Yamaguchi University, Ube, Yamaguchi, Japan

Paper No. IMECE2009-12073, pp. 27-29; 3 pages
  • ASME 2009 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology Engineering
  • Lake Buena Vista, Florida, USA, November 13–19, 2009
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4375-8 | eISBN: 978-0-7918-3863-1
  • Copyright © 2009 by ASME


The authors have developed Optical Coherence Straingraphy (OCS) as a visualizing technique of tissue strain distribution, by means of deformation of speckle pattern obtained by Optical Coherence Tomography. In this study, ex vivo OCS imaging experiment was carried out using atherosclerotic plaques of WHHL rabbit, compared with simulated results of histologically image-based FEM. Consequently, strain pattern obtained by OCS has qualitative agreement with simulated results. Therefore, it was confirmed that OCS could diagnose biomechanical properties of atherosclerotic plaque tomographically.

Copyright © 2009 by ASME



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