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Experimental Study and CFD Analysis of the Volumatic® Spacer

[+] Author Affiliations
Sofia Abreu, Luís Silva, Senhorinha F. C. F. Teixeira

University of Minho, Guimarães, Portugal

Henedina Antunes

S. Marcos Hospital, Braga, Portugal

Helena Marques, Nuno Ramalhete

University of Lisbon, Lisboa, Portugal

Paper No. BioMed2008-38068, pp. 97-103; 7 pages
doi:10.1115/BioMed2008-38068
From:
  • ASME 2008 3rd Frontiers in Biomedical Devices Conference
  • ASME 2008 3rd Frontiers in Biomedical Devices Conference
  • Irvine, California, USA, June 18–20, 2008
  • Conference Sponsors: Nanotechnology Institute
  • ISBN: 0-7918-4833-7 | eISBN: 0-7918-3823-4
  • Copyright © 2008 by ASME

abstract

The aim of the present study was to evaluate the performance of Ventilan® coupled to the Volumatic® spacer. An experimental study was conducted using the four stage Multistage Liquid Impinger (MSLI). This enabled the observation that half of the pharmacological dose is retained within the body of the spacer. Therefore, the air flow inside the spacer was studied, along the respiratory cycle, using Fluent™. Several recirculation regions were observed inside the spacer that may influence the aerosol flow and also the deposition of the drug.

Copyright © 2008 by ASME

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