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Fluidic Engineering Challenges in the Development of an Electronic-Based DNA Identification System

[+] Author Affiliations
D. Chafin, R. Murante, R. J. Greco, J. Hainon, S. Seabridge, K. VanDerMeid, C. Tiller, D. Michael Connolly

Integrated Nano-Technologies, LLC, Henrietta, NY

Paper No. ICMM2004-2314, pp. 1-6; 6 pages
doi:10.1115/ICMM2004-2314
From:
  • ASME 2004 2nd International Conference on Microchannels and Minichannels
  • ASME 2nd International Conference on Microchannels and Minichannels
  • Rochester, New York, USA, June 17–19, 2004
  • Conference Sponsors: Nanotechnology Institute
  • ISBN: 0-7918-4164-2
  • Copyright © 2004 by ASME

abstract

Integrated Nano-Technologies, LLC (INT) has spent the last three and a half years developing a novel electronic based DNA identification system. In addition to combining DNA with microelectronics to form sensors that respond to, and identify DNA sequences in target organisms; this system relies heavily on the manipulation and delivery of small volumes of fluids. These fluids facilitate both the biological and chemical reactions required by the devices processes. The Company has encountered fluidic engineering challenges throughout the development of the system including: • pump accuracy and delivery; • material incompatibilities; • adhesive intrusion; • reaction waste collection; • micro mixing/channel design. In this presentation, the challenges and the approaches taken to overcome them will be presented, as well as a device overview.

Copyright © 2004 by ASME
Topics: DNA

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