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Manipulation of Individual Beads Using Submicron Magnetic Features in Microfluidic Channels

[+] Author Affiliations
Zhengchun Peng, Peter Hesketh, Paul Joseph

Georgia Institute of Technology, Atlanta, GA

Paper No. MicroNano2008-70169, pp. 503-507; 5 pages
doi:10.1115/MicroNano2008-70169
From:
  • 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems
  • 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems
  • Clear Water Bay, Kowloon, Hong Kong, June 3–5, 2008
  • Conference Sponsors: Nanotechnology Institute
  • ISBN: 0-7918-4294-0 | eISBN: 0-7918-3819-6
  • Copyright © 2008 by ASME

abstract

We developed a method to manipulate submicron paramagnetic beads in such a way that we not only collectively confine the beads to a specific location inside a microfluidic channel, but also control the positions of the individual beads. The manipulation was based on the attraction force between moving paramagnetic beads and stationary ferromagnetic (e.g., NiFe) features subjected to an external uniform magnetic field. The position of trapped beads was investigated by both theoretical prediction and experimental validation. The control of individual beads in large number allowed us to adjust the number density of beads on a surface as well as optimize the design of the detection elements for the beads.

Copyright © 2008 by ASME

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