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The Effect of Surface Nano/Micro-Texturing on Escherichia Coli Cell Adhesion

[+] Author Affiliations
Hengyu Wang, Jeong-Hwan Kim, Min Zou, Steve Tung, Jin-Woo Kim

University of Arkansas, Fayetteville, AR

Paper No. MicroNano2008-70146, pp. 155-157; 3 pages
  • 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems
  • 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems
  • Clear Water Bay, Kowloon, Hong Kong, June 3–5, 2008
  • Conference Sponsors: Nanotechnology Institute
  • ISBN: 0-7918-4294-0 | eISBN: 0-7918-3819-6
  • Copyright © 2008 by ASME


Control of cell-to-surface adhesion has significant impacts on various biological and biomedical applications. In this study, the adhesion of Escherichia coli (E. coli) cells on nano/micro-textured surfaces produced by a unique surface texturing technique, aluminum-induced crystallization (AIC) of amorphous silicon (a-Si), was studied in order to control E. coli cell adhesion on glass substrates in an E. coli-based whole-cell chemical sensor. It was found that textured surfaces significantly enhanced cell-to-surface adhesion. Among the textured surfaces, nano/micro-textured surfaces showed advantage over micro-textured surfaces on the cell-to-surface adhesion. Study of the cell-to-surface adhesion mechanism suggests that the cell adhesion efficiency was controlled by the particle density of the textured surfaces.

Copyright © 2008 by ASME



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