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Nanoporous Polymeric Grating-Based Biosensors

[+] Author Affiliations
Tieyu Gao

Xi’an Jiaotong University, Xi’an, Shaanxi, China

Vincent Hsiao, Yue Bing Zheng, Tony Jun Huang

The Pennsylvania State University, University Park, PA

Paper No. IMECE2010-40928, pp. 1453-1456; 4 pages
doi:10.1115/IMECE2010-40928
From:
  • ASME 2010 International Mechanical Engineering Congress and Exposition
  • Volume 5: Energy Systems Analysis, Thermodynamics and Sustainability; NanoEngineering for Energy; Engineering to Address Climate Change, Parts A and B
  • Vancouver, British Columbia, Canada, November 12–18, 2010
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4429-8
  • Copyright © 2010 by ASME

abstract

We demonstrate the utilization of an interferometrically created nanoporous polymeric gratings as a platform for biosensing applications. Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings was fabricated by combining holographic interference patterning and APTES-functionalization of pre-polymer syrup. The successful detection of multiple biomolecules indicates that the biofunctionalized nanoporous polymeric gratings can act as biosensing platforms which are label-free, inexpensive, and applicable as high-throughput assays.

Copyright © 2010 by ASME

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