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Modeling Targeted Drug Delivery in a Vascular Network

[+] Author Affiliations
Yaling Liu, Kytai Nguyen, Manohara Mariyappa, Samar Shah, Jifu Tan

University of Texas at Arlington, Arlington, TX

Paper No. NEMB2010-13075, pp. 363-364; 2 pages
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME


Nanomedicine dosages are selected in part based on the competing goals of maximizing death of malignant cells while minimizing damage to healthy cells. Determination of proper nanomedicine dosage and concentration is difficult to due the lack of understanding of nanoparticle targeted delivery process in complex vascular environment. This paper presents a continuum model of the transportation and targeted deposition of nanoparticles in a vascular network, which is an essential component of a multi-scale targeted delivery predictive tool being developed.

Copyright © 2010 by ASME



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