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Knockdown of SHP-1 Enhances Endothelial Cell Retention for Vascular Regeneration

[+] Author Affiliations
Brandon J. Tefft, Adrian M. Kopacz, Wing Kam Liu, Shu Q. Liu

Northwestern University, Evanston, IL

Paper No. NEMB2010-13233, pp. 351-352; 2 pages
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME


Atherosclerosis is the leading cause of morbidity and mortality in the developed world. A common treatment option is arterial bypass surgery, which requires the use of a vascular graft. Autologous vein is the current gold standard for use as a vascular graft; however, donor site morbidity and inconsistent availability have provided an impetus to explore alternative graft sources.

Copyright © 2010 by ASME



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