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Simultaneous Measurements of Diffusion Coefficient on Cell Membrane by Fluorescence Photobleaching and Single Quantum Dot Tracking Techniques

[+] Author Affiliations
Donghee Lee, Choonho Park, Jung Kyung Kim

Kookmin University, Seoul, Korea

Jeonghoon Lee

Seoul National University, Seoul, Korea

Paper No. NEMB2010-13027, pp. 329-330; 2 pages
doi:10.1115/NEMB2010-13027
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

The diffusion of biomolecules in plasma membranes is the key mechanism of their transportation. Lipid rafts, which are diffused on a plasma membrane, carry receptors and proteins. Receptors become the passages where viruses invade, and proteins play an important role in signaling and controlling functions of cells. If we know the characteristics of biomolecular motility and structural differences between normal cells and diseased cells, we could find out how to treat the disease. So, it is very important to develop the method which analyzes the dynamic biomolecular movement in the cell membrane.

Copyright © 2010 by ASME

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