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Multiscale Modeling of Protein Crystals: Application to Tetragonal Lysozyme

[+] Author Affiliations
Amir Reza Zamiri, Suvranu De

Rensselaer Polytechnic Institute, Troy, NY

Paper No. NEMB2010-13170, pp. 295-296; 2 pages
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME


Recently, protein crystals have emerged as promising bionanoporous materials for different applications including highly selective biocatalysis, biosensing, bioseparation, vaccine formulation, and drug delivery. The environmental working conditions require the protein crystals to be both chemically and mechanically stable. The structure, behavior, and mechanical properties of protein crystals play an important role in the performance and life cycle of these materials [1,2]. In this work we introduce a strategy for evaluating the mechanical response of protein crystals with the tetragonal lysozyme crystal as a model.

Copyright © 2010 by ASME



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