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Gas-Phase Production of Multifunctional Composite Nanoparticles by Photoinduced Chemical Vapor Deposition

[+] Author Affiliations
Adam Boies, Pingyan Lei, Steven Girshick

University of Minnesota, Minneapolis, MN

Jeff Roberts

Purdue University, West Lafayette, IN

Paper No. NEMB2010-13181, pp. 223-224; 2 pages
doi:10.1115/NEMB2010-13181
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

Nano-scale materials and devices allow for unique interactions that are not possible at larger scales. Magnetic particles below a critical size (∼10 nm) demonstrate distinctive behavior known as superparamagnetism, where particles do not exhibit any net magnetic force outside the presence of an external magnetic field. However, within an alternating magnetic field, as in a magnetic resonance imaging (MRI) machine, superparamagnetic particles give off heat as a result of Brownian and Neélian relaxation. Heat produced by the shifting pole orientation can raise the temperature of the tissue sufficient to cause cell death through necrosis or apoptosis [1]. Additionally, combinations of electrically conductive and insulating materials within a single nanoparticle give rise to surface plasmon resonance. The resonance of the plasmon absorption can be tuned based on the relative thicknesses of the two layers. These particles can be used to thermally ablate cancer cells if the resonance is tuned to absorb light from an infrared laser. The penetrating ability of the nanoparticles combined with their capacity to kill cells make them excellent candidates for treatment of conditions such as brain tumors and prostate cancer.

Copyright © 2010 by ASME

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