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Material Study for Electrowetting-Based Multi-Microfluidics Array Printing of High Resolution Tissue Construct With Embedded Cells and Growth Factors

[+] Author Affiliations
Chris G. Geisler, Peter I. Lelkes, Jack G. Zhou

Drexel University, Philadelphia, PA

David M. Wootton

Cooper Union, New York, NY

Richard Fair

Duke University, Durham, NC

Paper No. NEMB2010-13048, pp. 191-193; 3 pages
doi:10.1115/NEMB2010-13048
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

Tissue engineering (TE) is evolving as a potential solution for repair and reconstruction of diseased or damaged tissues. TE faces major manufacturing challenges: manufacturing techniques are needed to mimic tissue and extra cellular matrix (ECM) architecture, with high resolution (less than 10 μm) for tissues such as myocardium (heart muscle), blood vessels, bone or nerves; innovative methods are needed for delivery of cells and growth factors into scaffolds; and manufacturing techniques are needed to create vascular structure in tissue construct; lack of nutrient transport currently limits the size and cellular content of implants.

Copyright © 2010 by ASME

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