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Characterization of a Magnetic Microactuator for Manipulating Nanoparticles in Gene Delivery Applications

[+] Author Affiliations
Eva Flick, Hans H. Gatzen

Leibniz Universitaet Hannover, Garbsen, Germany

Wenzhong Li, Gustav Steinhoff

University of Rostock, Rostock, Germany

Jonas Norpoth, Christian Jooss

Georg-August-Universitaet Goettingen, Goettingen, Germany

Paper No. NEMB2010-13025, pp. 189-190; 2 pages
doi:10.1115/NEMB2010-13025
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

Magnetically driven gene delivery provides a valuable approach for a single cell transfection. Therapeutic genes can be manipulated by conjugating them to magnetic nanoparticles. The magnetic force required for the manipulation of such complexes can be provided by an electromagnetic micro-actuator designed as micro pole row. The analytical calculations, simulations, and the thin-film fabrication of this micro pole row were carried out previously [1]. This paper presents characterization results of the first microactuator fabrication batch.

Copyright © 2010 by ASME

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