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Nanomedical Applications of Optofluidics

[+] Author Affiliations
David Erickson

Cornell University, Ithaca, NY

Paper No. NEMB2010-13381, pp. 159-160; 2 pages
doi:10.1115/NEMB2010-13381
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

In this talk I will discuss some of the nanomedical applications of optofluidic systems. As will be demonstrated such devices hold significant promise for improving on the state of the art in detection sensitivity as well as enable entirely new modalities for molecular analysis. Two example platforms will be discussed. The first of these will be our Nanoscale Optofluidic Sensor Arrays which comprise of a series of 1D evanescently coupled linear optical resonators. In addition to demonstrating both nucleic acid (Dengue virus) and immunological detection (Interleukins), I will show how optical forces can be used to increase the functionality of these devices including single molecule analysis. The second platform described is a method for performing surface enhanced raman spectroscopy (SERS) on a chip. A unique ligase detection reaction based assay will be demonstrated to show the unique advantages of the approach.

Copyright © 2010 by ASME
Topics: Nanomedicine

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