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Design and Optimization of a Nanotip Sensor via Immersed Molecular Electrokinetic Finite Element Method

[+] Author Affiliations
Adrian M. Kopacz, Wing K. Liu

Northwestern University, Evanston, IL

Jae-Hyun Chung

University of Washington, Seattle, WA

Paper No. NEMB2010-13299, pp. 59-60; 2 pages
doi:10.1115/NEMB2010-13299
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

A critical challenge in the field of medicine is to develop a low cost sensor competent of detecting specific bacterial pathogens via a precise deoxyribonucleic acid (DNA) sequence. In order to identify such biological agents in a patient’s blood or other bodily fluids at the onset of infection, detection of specific pathogen genomic DNA is considered a reliable approach. Current techniques involving multiplex DNA/RNA detection arrays or immunoassays [1] require cumbersome sample preparation, aggressive nucleic acid amplification protocols and must be operated by trained personnel. To overcome the aforementioned obstacles, a time-dependent dielectrophoretic force driven sensor consisting of nanostructured tip is being developed.

Copyright © 2010 by ASME

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