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Gold Nanoparticle Self Assembly on Diblock Copolymers for Application as Biomolecular Sensors

[+] Author Affiliations
Sarah M. Adams, Regina Ragan

University of California, Irvine, Irvine, CA

Paper No. NEMB2010-13126, pp. 21-22; 2 pages
doi:10.1115/NEMB2010-13126
From:
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology
  • Houston, Texas, USA, February 7–10, 2010
  • Conference Sponsors: ASME Nanotechnology Council
  • ISBN: 978-0-7918-4392-5 | eISBN: 978-0-7918-3866-2
  • Copyright © 2010 by ASME

abstract

Current efforts in medical diagnostic technology focus toward developing biological sensors with the capacity for detecting trace quantities of specified organic molecules. In this study, metallic nanoparticles were investigated for the development of field-enhanced chemical and biological detection devices with the capacity to achieve single-molecule level detection resulting from surface enhanced Raman scattering (SERS) associated with closely spaced noble metal nanostructures.[1, 2] Localized surface plasmon resonance (LSPR) sensors likewise benefit from the incorporation of ordered metal nanoparticles on surfaces, providing increased shift in minimum of reflectivity with biological binding event (figure 1).[3]

Copyright © 2010 by ASME

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