Full Content is available to subscribers

Subscribe/Learn More  >

Modeling of a Novel Multi-Jet Emitter for ESI-MS Applications

[+] Author Affiliations
A. K. Sen, J. Darabi

University of South Carolina

D. R Knapp

Medical University of South Carolina

Paper No. IMECE2006-14401, pp. 7-16; 10 pages
  • ASME 2006 International Mechanical Engineering Congress and Exposition
  • Advances in Bioengineering, Biomedical and Safety Systems
  • Chicago, Illinois, USA, November 5 – 10, 2006
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4772-1 | eISBN: 0-7918-3790-4
  • Copyright © 2006 by ASME


This paper presents the concept and simulation of a novel multiple electrospray emitters for electrospray ionization mass spectrometric (ESI-MS) applications. The proposed emitter is based on an array of carbon nanofibers (CNF) vertically grown around the orifice of a microscale thermoplastic capillary. The electrospray ionization process is simulated using a CFD code that utilizes Taylor-Melcher leaky-dielectric formulations for the electrohydrodynamics and volume-of-fluid (VOF) method for tracking the interface. The modeling results predict that under steady state conditions, individual cone-jets are established around each of the CNFs resulting in an array of electrosprays. Effects of several design and operational parameters on the electrospray performance are thoroughly investigated. The results of the present study will facilitate design, fabrication and experiments using the CNF emitter. Higher spray current and lower jet diameter indicate that the proposed emitter can perform equivalent to nanospray emitters exhibiting improved MS sensitivity while using a microscale orifice. Use of microscale orifice benefits in terms of higher sample throughput and eliminates potential clogging problem inherent in nanoscale capillaries. Overall, the proposed emitter is believed to be a suitable candidate for ESI-MS applications.

Copyright © 2006 by ASME
Topics: Modeling



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In