Full Content is available to subscribers

Subscribe/Learn More  >

Identification of Multi-Channel Cardiovascular System Using Dual-Pole Laguerre Basis Functions for Assessment of Aortic Flow and TPR

[+] Author Affiliations
Jin-Oh Hahn, H. Harry Asada

Massachusetts Institute of Technology, Cambridge, MA

Andrew T. Reisner

Massachusetts General Hospital, Boston, MA

Paper No. IMECE2007-41186, pp. 141-150; 10 pages
  • ASME 2007 International Mechanical Engineering Congress and Exposition
  • Volume 9: Mechanical Systems and Control, Parts A, B, and C
  • Seattle, Washington, USA, November 11–15, 2007
  • Conference Sponsors: ASME
  • ISBN: 0-7918-4303-3 | eISBN: 0-7918-3812-9
  • Copyright © 2007 by ASME


This paper presents a novel method to identify the multichannel cardiovascular system using two distinct peripheral blood pressure signals. The method can characterize the distinct arterial path dynamics that shape each of the blood pressure signals, and recover the common aortic flow signal fed to them. A Laguerre series data compression technique is used to obtain a compact representation of the cardiovascular system, whose coefficients are identified using the multi-channel blind system identification. A Laguerre model de-convolution algorithm is developed to stably recover the aortic flow signal. Persistent excitation, model identifiability, and asymptotic variance are analyzed to quantify the method’s validity and reliability. From the identified Laguerre series coefficients of the cardiovascular dynamics, mean aortic flow and total peripheral resistance are estimated. Experimental results based on 7,000 data segments obtained from 9 swine models show that the waveform of the aortic flow is stably recovered from peripheral blood pressure signals and that the cardiovascular dynamics can be identified very reliably for all the swine models under diverse physiologic conditions. In addition, the use of the identified cardiovascular dynamics results in the improvement in estimating the mean aortic flow and total peripheral resistance by 60% and 45% in terms of the R2 value, compared to their standard counterparts.

Copyright © 2007 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In