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Graft Healing of Stretched ePTFE Implanted Within a Baboon Model

[+] Author Affiliations
James R. Costello, Don P. Giddens, Stephen R. Hanson

Georgia Institute of Technology, Atlanta, GA

Changyi Chen

Emory University, Atlanta, GA

Paper No. IMECE2002-32784, pp. 257-258; 2 pages
  • ASME 2002 International Mechanical Engineering Congress and Exposition
  • Advances in Bioengineering
  • New Orleans, Louisiana, USA, November 17–22, 2002
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-3650-9 | eISBN: 0-7918-1691-5, 0-7918-1692-3, 0-7918-1693-1
  • Copyright © 2002 by ASME


Arterial grafts need to exhibit two properties: a flow surface with low thrombogenicity and minimal intimal thickening. For well over thirty years, researchers focused their attention upon the healing properties of graft material. Beginning with Wesolowski’s 1961 work, researchers concluded that porous synthetic grafts demonstrated improved healing properties (1). Most recently, Clowes, et al., documented that ePTFE with a nominal porosity of 60μm healed atone month with complete endothelial coverage, uniformly distributed pseudointimal growth, and improved intimal stability (2). These results contrasted to what was found when porosity was deceased to an internodal distance of 10 or 30 μm.

Copyright © 2002 by ASME



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