Full Content is available to subscribers

Subscribe/Learn More  >

Extraction of Flow Information in Choriocapillaris in Human Eyes From ICG Dye Angiography Images

[+] Author Affiliations
L. Zhu, Q. He, C. H. von Kerczek, L. D. T. Topoleski, R. W. Flower

University of Maryland Baltimore County, Baltimore, MD

Paper No. IMECE2002-33067, pp. 147-151; 5 pages
  • ASME 2002 International Mechanical Engineering Congress and Exposition
  • Advances in Bioengineering
  • New Orleans, Louisiana, USA, November 17–22, 2002
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-3650-9 | eISBN: 0-7918-1691-5, 0-7918-1692-3, 0-7918-1693-1
  • Copyright © 2002 by ASME


Indocyanine green (ICG) dye angiography has been used by ophthalmologists as a useful tool for routine examination of the vasculature of the choroid in human eyes. ICG dye angiography is performed by venous injecting of ICG dye, which is delivered to different vascular structures in the eyes at different times. A multi-spectral fundus camera is used to take the dye intensity images of the eye at a speed of thirty images per second. In this study, a new approach is developed to extract information of velocity distribution in the choriocapillaris and its feeding blood vessels from the ICG dye angiograms. The ICG dye intensity rise and decay curves are constructed from the ICG dye images at each image pixel location in the choriocapillaris. It is shown that the magnitude of the local velocity in the choriocapillaris is proportional to the transient of the ICG dye intensity curve. The approach allows the determination of the absolute value of the velocity in the choriocapillaris and is calibrated by the image data at two axial locations of a straight blood vessel of uniform cross-section area. The velocity image of the entire choriocapillaris is then constructed. This approach could be used in clinical applications for diagnostic purposes since it provides detailed quantified flow information in human eyes.

Copyright © 2002 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In