Full Content is available to subscribers

Subscribe/Learn More  >

Two-Photon Polymerization Technique for Bio-Applications

[+] Author Affiliations
Aleksandr V. Ovsianikov, Boris N. Chichkov

Laser Zentrum Hannover e.V.

Paper No. IMECE2005-79873, pp. 105-108; 4 pages
  • ASME 2005 International Mechanical Engineering Congress and Exposition
  • Manufacturing Engineering and Materials Handling, Parts A and B
  • Orlando, Florida, USA, November 5 – 11, 2005
  • Conference Sponsors: Manufacturing Engineering Division and Materials Handling Division
  • ISBN: 0-7918-4223-1 | eISBN: 0-7918-3769-6
  • Copyright © 2005 by ASME


We will report on the recently developed two-photon polymerization (2PP) technique for biological applications. 2PP of photosensitive inorganic-organic hybrid polymers (ORMOCERs) is applied for the fabrication of 3D scaffolds, micro-and nanostructures. ORMOCERs have negative resist behaviour and can be used as storage-stable, liquid photopolymerizable resins. When Ti:sapphire femtosecond laser pulses are tightly focused into the volume of this resin (which is transparent in the infrared) they initiate 2PP process transferring liquid into the solid state. This allows the fabrication of any computer-generated 3D structure by direct laser “recording” into the volume of this material. ORMOCERs demonstrate excellent cell adherence and cell growth rate comparable to that of Extracellular matrix. With 2PP technique there are no limits in complexity of the 3D scaffold structures which can be fabricated with the resolution of 100 nm.

Copyright © 2005 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In