Full Content is available to subscribers

Subscribe/Learn More  >

A Novel Device for the Microindentation of Soft Biomaterials With Application to Aortic Valve Leaflets

[+] Author Affiliations
Matthew G. Doyle, Craig A. Simmons

University of Toronto, Toronto, ON, Canada

Moussa Chehade

Johns Hopkins University, Baltimore, MD

Paper No. SBC2013-14733, pp. V01AT04A023; 2 pages
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME


Microscale mechanical properties of soft biomaterials, such as heart valves, are of interest to researchers studying the effects of matrix mechanical properties on cell function. Measurements at the microscale, on the order of 1–500 μm, are representative of the mechanical properties experienced by the cells in their environment (1). In contrast, other methods like conventional tensile/compression testing and atomic force microscopy provide macroscale and nanoscale properties, respectively, that do not reflect the local micromechanical environment at the cellular scale.

Copyright © 2013 by ASME
Topics: Biomaterials , Valves



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In