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Aneurismal Arteries are Vulnerable to Mechanical Buckling

[+] Author Affiliations
Hai-Chao Han, Avione Y. Lee, Ramsey H. Shadfan, Yangming Xiao

University of Texas at San Antonio – University of Texas Health Science Center at San Antonio, San Antonio, TX

Paper No. SBC2013-14192, pp. V01AT04A003; 2 pages
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME


Rupture of aneurysms is a leading cause of death in the United States. Extensive biomechanical studies have shown that mechanical stress in aneurysm walls plays a critical role in the rupture of aneurysms. Highly elevated local stress and degraded aneurismal walls are believed to make aneurysms vulnerable to rupture [1–3]. Asymmetric aneurysms with irregular shape and wall thickness are vulnerable to rupture. Aneurismal arteries are often tortuous such as in the Loeys-Dietz syndrome [4], but the mechanism is unclear.

Copyright © 2013 by ASME



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